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☆ Mayan Toledano’s vibrant photographs of queer life in Mexico City
▼ + stars: | 2023-11-07 | by ( Jacqui Palumbo | ) edition.cnn.com time to read: +7 min

Toledano, who is primarily based in New York, found a welcoming second home in Mexico City in 2018 through a circle of queer and trans creatives that expanded with each visit. Jovana, Sheila, Karla and Andrea, 2019 Mayan Toledano“The getting-ready part is sometimes the party,” Toledano explained in a phone interview. In Mexico City, Toledano’s images became a mix of both candid and staged moments. Greta, Aine, Mar and Zury on the Wall at Magia Ilegal, Ixtapaluca Mayan Toledano“That was a moment of stillness. Havi at Home, 2019 Mayan ToledanoAn American friend of Havi’s had helped organize crowdfunding for the surgery, according to Toledano.

Persons: Mayan Toledano, Karla, Toledano, glammed, Karla’s, Jose Cuervo, Sheila, Andrea, ” Toledano, Maria Mariposa, Uma, Ada, Maria Isas, it’s, “, ”, Bella Hadid, Paris Hilton, Maria, Aine, Toledano’s, Havi, Havi’s, ‘, “ Protagonism, ” Havi, ” Seb, Sebastian Organizations: CNN, Nike, Damiani Locations: Mexico City, New York, Mexico, Polanco, Paris, Greta, Zury, ”, “

☆ AstraZeneca's Tagrisso-chemo combo results raise bar for J&J cancer drug-analysts
▼ + stars: | 2023-09-11 | by ( Maggie Fick | ) www.reuters.com time to read: +2 min

LONDON, Sept 11 (Reuters) - Data released on Monday by AstraZeneca (AZN.L) from a late-stage trial combining its blockbuster cancer drug Tagrisso with chemotherapy to treat a type of lung cancer raises the bar for Johnson & Johnson's (JNJ.N) rival treatment, analysts said. A brief summary from the Phase 3 trial, called FLAURA2, was released in May, and the detailed data was presented on Monday in Singapore at the World Conference on Lung Cancer. The FLAURA2 trial showed that when adding chemotherapy to Tagrisso, the risk of disease progression or death is reduced by 38% when compared to Tagrisso alone. "With the strong FLAURA-2 data in hand and likely included in treatment guidelines soon, the hurdle is now pretty high in our view for MARIPOSA," the UBS note read. Barclays analysts said the FLAURA2 trial data presented on Monday included doctor and patient surveys that showed a strong preference for the convenience of a single therapy compared with combinations.

Persons: Johnson, Pascal Soriot, Michel Demare, Soriot, Maggie Fick, Emelia Sithole Organizations: AstraZeneca, Lung Cancer, Barclays, UBS, Reuters, Thomson Locations: Singapore, British, MARIPOSA

☆ UBS upgrades Big Pharma stock after shares drop on poor drug results
▼ + stars: | 2023-07-13 | by ( Ganesh Rao | ) www.cnbc.com time to read: +3 min

UBS upgraded AstraZeneca 's stock to a "buy" rating despite the drugmaker's trial of a lung cancer medication recently delivering poor results. The investment bank said the subsequent drop in the pharma giant's stock price now meant that "investors can come back to the stock for the performance of in-market products." London-listed shares of AstraZeneca dropped by 8% in a single day, the most in years, after releasing the results of the "TropionLung01" trial for drug candidate "Dato-DXd." UBS expects shares of AstraZeneca to rise by 27% to £13 ($16.8) a share over the next 12 months. These include Imfinzi, a drug for bile duct or gallbladder cancer, and Tagrisso, a treatment for non-small cell lung cancer in adults.

Persons: Michael Leuchten, UBS Michael Leuchten AZN Organizations: UBS, AstraZeneca, pharma, DXd, FDA, Johnson Locations: London, Swiss, Tagrisso

California is enduring more severe winter weather as storms continue to unleash unusual snowfall and strong winds across the state, damaging highways and roads and trapping some residents in their homes. Gavin Newsom on Wednesday evening declared a state of emergency in 13 counties affected by the storms. Disaster response and relief will be provided to the counties of Amador, Kern, Los Angeles, Madera, Mariposa, Mono, Nevada, San Bernardino, San Luis Obispo, Santa Barbara, Sierra, Sonoma and Tulare. The state's emergency agency and private weather forecasters in January said that damage from weeks of storms and flooding in California could surpass $1 billion. In the San Bernardino Mountains, snowfall blocked roads and stranded residents in their homes as crews worked urgently to clear the roads.

☆ California sees extensive storm damage as weather calms
▼ + stars: | 2023-01-18 | by ( The Associated Press | ) www.nbcnews.com time to read: +2 min

Light rain and snow showers lingered Tuesday in some areas across California, but the skies were finally largely clear. A shot of precipitation from a quick system was predicted for Wednesday or Thursday, followed by a dry period, the National Weather Service said. More than 70 residents were evacuated by helicopter, but a handful have refused to leave, according to the Ventura County Sheriff’s Office. “We’ve had enough rain for now and a long time to come.”The amount of rain and snow across the state has been staggering. The San Francisco “water year” to date — since Oct. 1, 2022 — has recorded 21.75 inches of rain, making it the sixth-wettest water year on record, the National Weather Service said.

☆ Tackling the threat of mudslides in soaked California
▼ + stars: | 2023-01-16 | by ( The Associated Press | ) www.nbcnews.com time to read: +7 min

Matt Udkow / Santa Barbara County Fire Department via AP fileWhy is California prone to mudslides? Since New Year’s Eve, the California Department of Conservation’s landslide mapping team has documented more than 300 landslides. Lancaster said California has dramatically increased its efforts to identify hotspots since the Montecito mudslides. After the 2018 mudslides hit Montecito, the Los Angeles Times reported that debris basins above the community were undersized and hadn’t been sufficiently emptied. The organization hired an engineering company to map the canyons and installed debris nets.

Two people died in a rock slide earlier this week at the Yosemite National Park, according to the local county sheriff’s office. On Friday evening, the park announced another closure at Big Oak Flat Road, east of Foresta, due to another rockfall incident. As of Saturday morning, Big Oak Flat Road remains closed. According to the Yosemite National Park, although uncommon, the Yosemite Valley can experience numerous rockfalls each year. According to the U.S. National Park Service, the Yosemite National Park welcomed 3.3 million visitors in 2021, making it one out of the 25 most visited national parks in the nation.

☆ A leaked video exemplifies what Black migrants endure in US detention centers
▼ + stars: | 2022-03-26 | by ( John Washington | José Olivares | ) www.businessinsider.com time to read: +30 min

A leaked video obtained by Insider shows guards violently tackling a Black asylum seeker at a Louisiana detention center. Detainees and immigration lawyers say there is a disturbing and overlooked problem of anti-Black racism in immigration detention. In January, Representative Cori Bush (D-MO) and Senator Cory Booker (D-NJ) called for a "holistic review of the disparate treatment of Black migrants." Across the state, eight new immigration detention centers have been opened in the past three years – all privately run. In just Texas and Louisiana, 11 separate facilities in recent years have shifted from prisons or jails to immigration detention centers.

Persons: Brandon, Sarah Loicano, Loicano, he'd, Anna Watts, They're, Allen Morris, Morris, he's, —, Cori Bush, Cory Booker, Romelia Solano, Solano, wasn't, It's, Eunice Cho, Cho, Sami Disu, Trump, Biden, Joe Biden, Shah, Black, I've, Jim Crow, Winn, Sarah Decker, Decker, they're, Ellis, Rebekah Wolf, Critics, Wolf, RAICES, isn't, That's, Acheleke, Fuanya, kneeled, fingerprinted, Sophia Diez, Zhang Organizations: FIFA, LaSalle Correctional Center, Salvadoran, Brandon, LaSalle Detention, LaSalle Corrections, . Immigration, Customs Enforcement, ICE, Department of Homeland Security, Office, Customs, Border Patrol, LaSalle, and Immigrant Center for Education, Legal Services, Human Rights Watch, Immigrants, American Friends Service Committee, Southern Poverty Law, Detention, Freedom, Mariposa, LaSalle Correctional, of Africana Studies, John Jay College of Criminal, Detention Watch Network, ACLU, New Orleans ICE Field Office, Winn Correctional Center, ICE Processing Center, RFK Human Rights, Civil Rights, Civil Liberties, Winn, US Naval, American Immigration Council, —, American Bar Association, Haitian Locations: Louisiana, Cameroon, LaSalle, Africa, West Africa, Brownsville , Texas, Caribbean, Mexico, Texas, New York, New Jersey, Glades, Louisiana , Louisiana, Kentucky, Black, U.S, COVID, Allen Parish, Texas , Louisiana , Arizona, Georgia, New Orleans, Asia, Angel, US, Guantánamo Bay, Cuba, New Mexico, Central America, South Asia, Eastern Europe, Central, South America, United States, American, Brandon

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